Article
Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila.
Nature - 10 Mar 1994
Tax F E, Yeargers J J, Thomas J H
Abstract excerpt
The lin-12 and glp-1 genes of Caenorhabditis elegans encode members of the Notch family of transmembrane proteins. Genetic studies indicate that the lin-12 and glp-1 proteins act as receptors in specific developmental cell interactions and that their functions are partially redundant. lin-12 glp-...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis
- Caenorhabditis elegans Proteins
- Calcium-Binding Proteins
- Chromosome Mapping
- DNA
- Drosophila
- Drosophila Proteins
- Epidermal Growth Factor
- Genetic Complementation Test
- Helminth Proteins
- Insect Hormones
- Intercellular Signaling Peptides and Proteins
- Intracellular Signaling Peptides and Proteins
- Jagged-1 Protein
- Ligands