Article
Prospects for admixture mapping of complex traits.
American journal of human genetics - 1 Jan 2005
McKeigue Paul M
Abstract excerpt
Admixture mapping extends to human populations the principles that underlie linkage analysis of an experimental cross. For detecting genes that contribute to ethnic variation in disease risk, admixture mapping has greater statistical power than family-linkage studies. In comparison with association studies, admixture mapping requires far fewer markers to search the genome and is less affected by allelic...
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