Article
Ethnic-difference markers for use in mapping by admixture linkage disequilibrium.
American journal of human genetics - 1 Mar 2002
Collins-Schramm Heather E, Phillips Carolyn M, Operario Darwin J, Lee Jane S, Weber James L, Hanson Robert L, Knowler William C, Cooper Richard, Li Hongzhe, Seldin Michael F
Abstract excerpt
Mapping by admixture linkage disequilibrium (MALD) is a potentially powerful technique for the mapping of complex genetic diseases. The practical requirements of this method include (a) a set of markers spanning the genome that have large allele-frequency differences between the parental ethnicities contributing to the admixed population and (b) an understanding of the extent of admixture in the study population....
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