Article
Intracellular retention of hepatitis B virus surface protein mutants devoid of amino-terminal pre-S1 sequences.
The Journal of general virology - 1 Feb 1994
Gallina A, De Koning A, Rossi F, Milanesi G
Abstract excerpt
To study the mechanism of L protein-mediated, intracellular (pre-Golgi) retention of hepatitis B virus (HBV) surface proteins, a collection of HBV preS-S open reading frame variants bearing wild-type or modified preS extensions was expressed in human cells. When the secretion phenotype of the corresponding proteins was analysed, all surface proteins with rearranged preS domains were found to be at least partially...
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