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Article

Epitope mapping of the PreS1 domain of the hepatitis B virus large surface protein.

Virology - 1 Jun 1990

Kuroki K, Floreani M, Mimms L T, Ganem D

Abstract excerpt

The large (L) surface glycoprotein of hepatitis B virus is an important component of the virion envelope derived from translation initiation at the 5' end of the PreS1 domain of the surface antigen open reading frame. Since key roles in virion assembly and infectivity have been postulated for this protein, further understanding of its structure and topology is important. To this end we have mapped the epitopes...

Topics

Antibodies, Monoclonal
Blotting, Western
Epitopes
Glycoproteins
Hepatitis B Surface Antigens
Hepatitis B virus
Humans
Mutation
Precipitin Tests
Protein Precursors
Transfection
Viral Envelope Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Virion

Source

Identifiers

PMID: 1693249
DOI: 10.1016/0042-6822(90)90032-m

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1693249-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Epitope mapping of the PreS1 domain of the hepatitis B virus large surface protein.PMID 1693249Read ↗

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