Article
A short linear sequence in the pre-S domain of the large hepatitis B virus envelope protein required for virion formation.
Journal of virology - 1 Dec 1997
Bruss V
Abstract excerpt
Envelopment of the hepatitis B virus (HBV) nucleocapsid depends on the large envelope protein L, which is expressed as a transmembrane polypeptide at the endoplasmic reticulum membrane. Previous studies demonstrated that the cytosolic exposure of the N-terminal pre-S domain (174 amino acids) of L was required for virion formation. N-terminal truncations of L up to Arg 103 were tolerated. To map sites in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
