Article
A short linear sequence in the pre-S domain of the large hepatitis B virus envelope protein required for virion formation.
Journal of virology - 1 Dec 1997
Bruss V
Abstract excerpt
Envelopment of the hepatitis B virus (HBV) nucleocapsid depends on the large envelope protein L, which is expressed as a transmembrane polypeptide at the endoplasmic reticulum membrane. Previous studies demonstrated that the cytosolic exposure of the N-terminal pre-S domain (174 amino acids) of L...
Topics
- Alanine
- Amino Acid Sequence
- Animals
- Asparagine
- Binding Sites
- COS Cells
- Gene Deletion
- Genetic Complementation Test
- Genome, Viral
- Hepatitis B Surface Antigens
- Hepatitis B virus
- Humans
- Molecular Sequence Data
- Mutagenesis
- Phenotype
- Proline
- Protein Precursors
- Structure-Activity Relationship