Article
The role of the insulin-like growth factor I receptor in the transformation by simian virus 40 T antigen.
Oncogene - 1 Mar 1994
Valentinis B, Porcu P L, Quinn K, Baserga R
Abstract excerpt
Balb/c 3T3 cells transformed by the tsA58 temperature-sensitive (ts) mutant of SV40 large T antigen, BalbA58 cells, grow in 1% serum at the permissive temperature of 34 degrees C but fail to grow at the restrictive temperature of 39.6 degrees C. Although incapable of growing, BalbA58 cells, in low serum at 39.6 degrees C, still synthesize DNA and tend to accumulate in the G2 phase of the cell cycle. Growth in 1%...
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