Article
The role of the insulin-like growth factor I receptor in the transformation by simian virus 40 T antigen.
Oncogene - 1 Mar 1994
Valentinis B, Porcu P L, Quinn K, Baserga R
Abstract excerpt
Balb/c 3T3 cells transformed by the tsA58 temperature-sensitive (ts) mutant of SV40 large T antigen, BalbA58 cells, grow in 1% serum at the permissive temperature of 34 degrees C but fail to grow at the restrictive temperature of 39.6 degrees C. Although incapable of growing, BalbA58 cells, in lo...
Topics
- 3T3 Cells
- Animals
- Antigens, Polyomavirus Transforming
- Cell Division
- Cell Line
- Cell Transformation, Viral
- DNA
- Insulin-Like Growth Factor I
- Mice
- Mice, Inbred BALB C
- Mutation
- Receptors, Somatomedin
- Temperature