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Article

Overexpression of yeast PAM1 gene permits survival without protein phosphatase 2A and induces a filamentous phenotype.

The Journal of biological chemistry - 4 Feb 1994

Hu G Z, Ronne H

Abstract excerpt

Protein phosphatase 2A (PP2A) is an essential enzyme which is present in all eukaryotic cells. PP2A has been implicated in regulating various metabolic processes and also in the control of cell cycle progression. In the yeast Saccharomyces cerevisiae, the catalytic subunit of PP2A is encoded by two duplicated genes, PPH21 and PPH22. A third related gene, PPH3, also contributes some PP2A activity. We have used a...

Topics

Amino Acid Sequence
Base Sequence
Blotting, Northern
Gene Expression
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Fungal
Genes, Fungal
Genes, Suppressor
Genotype
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multigene Family

Phenotype

Phosphoprotein Phosphatases

Protein Phosphatase 2

RNA, Messenger

Restriction Mapping

Saccharomyces cerevisiae

Sequence Homology, Amino Acid

Source

Identifiers

PMID: 8106383

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8106383-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Overexpression of yeast PAM1 gene permits survival without protein phosphatase 2A and induces a filamentous phenotype.PMID 8106383Read ↗

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