Article
The Saccharomyces SHP1 gene, which encodes a regulator of phosphoprotein phosphatase 1 with differential effects on glycogen metabolism, meiotic differentiation, and mitotic cell cycle progression.
Molecular and cellular biology - 1 Apr 1995
Zhang S, Guha S, Volkert F C
Abstract excerpt
The phosphoprotein phosphatase 1 (PP1) catalytic subunit encoded by the Saccharomyces GLC7 gene is involved in control of glycogen metabolism, meiosis, translation, chromosome segregation, cell polarity, and G2/M cell cycle progression. It is also lethal when overproduced. We have isolated strains which are resistant to Glc7p overproduction lethality as a result of mutations in the SHP1 (suppressor of high-copy...
Topics
- Base Sequence
- Cell Compartmentation
- Cell Differentiation
- Cell Nucleus
- Chromosomes, Fungal
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Lethal
- Genes, Suppressor