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Article

The cellular functions of the yeast lipin homolog PAH1p are dependent on its phosphatidate phosphatase activity.

The Journal of biological chemistry - 21 Dec 2007

Han Gil-Soo, Siniossoglou Symeon, Carman George M

Abstract excerpt

The Saccharomyces cerevisiae PAH1-encoded Mg2+-dependent phosphatidate phosphatase (PAP1, 3-sn-phosphatidate phosphohydrolase, EC 3.1.3.4) catalyzes the dephosphorylation of phosphatidate to yield diacylglycerol and Pi. This enzyme plays a major role in the synthesis of triacylglycerols and phospholipids in S. cerevisiae. PAP1 contains the DXDX(T/V) catalytic motif (DIDGT at residues 398-402) that is shared by...

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Identifiers

PMID: 17971454
DOI: 10.1074/jbc.M705777200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The cellular functions of the yeast lipin homolog PAH1p are dependent on its phosphatidate phosphatase activity.PMID 17971454Read ↗

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