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Article

The PAH1-encoded phosphatidate phosphatase of Yarrowia lipolytica differentially affects gene expression and lipid biosynthesis.

Biochimica et biophysica acta. Molecular and cell biology of lipids - 1 Dec 2024

Carmon Taylor, Hill Na'Taja, Sripathi Venkateswara R, Gossett Zachary B, Fakas Stylianos

Abstract excerpt

Yarrowia lipolytica is a model oleaginous yeast with a strong capacity for lipid accumulation, yet its lipid metabolic pathways and regulatory mechanisms remain largely unexplored. The PAH1-encoded phosphatidate (PA) phosphatase governs lipid biosynthesis by its enzymatic activity and regulating the transcription of genes involved in phospholipid biosynthesis. In this work, we examined the effect of the loss of...

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Identifiers

PMID: 39089641
DOI: 10.1016/j.bbalip.2024.159544
PMCID: PMC11380575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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