Article
Protein phosphatase 2A in Saccharomyces cerevisiae: effects on cell growth and bud morphogenesis.
Molecular and cellular biology - 1 Oct 1991
Ronne H, Carlberg M, Hu G Z, Nehlin J O
Abstract excerpt
We have cloned three genes for protein phosphatases in the yeast Saccharomyces cerevisiae. Two of the genes, PPH21 and PPH22, encode highly similar proteins that are homologs of the mammalian protein phosphatase 2A (PP2A), while the third gene, PPH3, encodes a new PP2A-related protein. Disruptions of either PPH21 or PPH22 had no effects, but spores disrupted for both genes produced very small colonies with few...
Topics
- Amino Acid Sequence
- Base Sequence
- Biological Evolution
- Cloning, Molecular
- DNA Mutational Analysis
- Gene Expression
- Molecular Sequence Data
- Morphogenesis
- Phenotype
- Phosphoprotein Phosphatases
- Protein Phosphatase 2