Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

Lancet (London, England) - 2 Oct 1993

Almind K, Bjørbaek C, Vestergaard H, Hansen T, Echwald S, Pedersen O

Abstract excerpt

Since relative or absolute insulin deficiency and insulin insensitivity are involved in the aetiology of non-insulin-dependent diabetes mellitus (NIDDM), we examined whether patients with NIDDM exhibit genetic variability in the coding region of insulin receptor substrate-1 (IRS-1), a candidate gene that is ubiquitous in insulin-sensitive and insulin-like growth factor 1 (IGF1) sensitive tissues, including those...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acids
Share to Base Sequence
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Phenotype

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 8104271
DOI: 10.1016/0140-6736(93)92694-o

Genes

IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.PMID 8104271Read ↗

Insulin receptor substrate-1 variants in non-insulin-dependent diabetes.Semantic proximity Read ↗

Variant sequences of insulin receptor substrate-1 in patients with noninsulin-dependent diabetes mellitus.Semantic proximity Read ↗

Novel allele of the insulin receptor substrate-1 bearing two non-conservative amino acid substitutions in a patient with noninsulin-dependent diabetes mellitus. Mutations in brief no. 130. Online.Semantic proximity Read ↗

Human insulin receptor substrate-1: variant sequences in familial non-insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease.Semantic proximity Read ↗

Expression of variant forms of insulin receptor substrate-1 identified in patients with noninsulin-dependent diabetes mellitus.Semantic proximity Read ↗

Molecular scanning for mutations in the insulin receptor substrate-1 (IRS-1) gene in Mexican Americans with Type 2 diabetes mellitus.Semantic proximity Read ↗

Codon 972 polymorphism of the insulin receptor substrate-1 gene in impaired glucose tolerance and late-onset NIDDM.Semantic proximity Read ↗

Common amino acid substitutions in insulin receptor substrate-4 are not associated with Type II diabetes mellitus or insulin resistance.Semantic proximity Read ↗

The mutation of insulin receptor substrate-1 gene in Chinese patients with non-insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.Semantic proximity Read ↗

Association testing of common variants in the insulin receptor substrate-1 gene (IRS1) with type 2 diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.