Article
The germline repertoire of T cell receptor beta-chain genes in multiple sclerosis patients from Spain.
Journal of neuroimmunology - 1 Aug 1993
Martínez-Naves E, Victoria-Gutiérrez M, Uría D F, López-Larrea C
Abstract excerpt
Recently several reports have described contradictory results after studying the association between restriction fragments length polymorphisms (RFLP) of T cell receptor (TcR) beta-chain genes and multiple sclerosis (MS). We studied the allelic, genotypic and haplotypic distribution of RFLPs of TcR beta chain gene segments C beta, V beta 8 and V beta 11 in 97 unrelated multiple sclerosis (MS) patients, 11 with...
Topics
- Alleles
- Autoradiography
- DNA Probes
- Disease Susceptibility
- Genotype
- Haplotypes
- Humans
- Multiple Sclerosis
- Nucleic Acid Hybridization
- Polymorphism, Restriction Fragment Length
- Receptors, Antigen, T-Cell, alpha-beta
