The CYP1A1 gene and cancer susceptibility.

doi:10.1016/1040-8428(93)90007-q

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Article

The CYP1A1 gene and cancer susceptibility.

Critical reviews in oncology/hematology - 1 Feb 1993

Kawajiri K, Nakachi K, Imai K, Watanabe J, Hayashi S

Abstract excerpt

A close correlation between cigarette smoking associated lung cancer incidence and an Msp I restriction fragment length polymorphism (RFLP) of the human P-450 1A1 (CYP1A1) gene was found in a Japanese population in terms of genotype frequency and cigarette dose. A Val/Ile codon difference in the...

Topics

Cytochrome P-450 Enzyme System
Genetic Linkage
Genetic Predisposition to Disease
Genotype
Humans
Incidence
Lung Neoplasms
Neoplasms
Polymorphism, Restriction Fragment Length
Smoking

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