Article
Cytochrome P450 CYP1A1 MspI polymorphism and lung cancer susceptibility.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 1996
Xu X, Kelsey K T, Wiencke J K, Wain J C, Christiani D C
Abstract excerpt
We conducted a case-control study of 207 lung cancer patients and 283 controls to estimate the association of the MspI polymorphism in the cytochrome P450 CYP1A1 gene with lung cancer. The analysis of the CYP1A1 gene polymorphism was performed by RFLP analysis of PCR-amplified DNA. The associatio...
Topics
- Aged
- Asbestos
- Case-Control Studies
- Confounding Factors, Epidemiologic
- Cytochrome P-450 CYP1A1
- Educational Status
- Environmental Exposure
- Female
- Gene Amplification
- Genetic Predisposition to Disease
- Heterozygote
- Homozygote
- Humans
- Japan
- Logistic Models
- Lung Neoplasms
- Male
- Middle Aged