Article
CYP1A1 polymorphisms and risk of lung cancer in the ethnic Kashmiri population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000
Shaffi Sheikh M, Shah Mohd Amin, Bhat Imtiyaz Ahmad, Koul Parvaiz, Ahmad Syed Nisar, Siddiqi Mushtaq A
Abstract excerpt
The CYP1A1 category of enzymes plays a central role in the metabolic activation of major tobacco carcinogens. Several polymorphisms within the CYP1A1 locus have been identified and have been shown to be associated with lung cancer risk, particularly in Asian populations. Here we focused on the influence of three polymorphisms on lung cancer in ethnic Kashmiris, genotyping 109 lung cancer cases and 163 healthy...
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