Article
The role of CYP1A1 Msp1 gene polymorphisms on lung cancer development in Turkey.
Tuberkuloz ve toraks - 1 Jan 2005
Demir Adalet, Altin Sedat, Demir Israfil, Köksal Vedat, Cetinçelik Umran, Dinçer Ibrahim
Abstract excerpt
Polymorphisms for genes encoding the metabolic enzymes cytochrome P450 1A1 (CYP1A1) might contribute to the variability in individual susceptibility to lung cancer. The role of CYP1A1 in lung carcinogenesis might be more important at low levels of exposure to carcinogens. In our study, CYP1A1 gene polymorphisms were investigated in healthy subjects and lung cancer patients in Turkish population. This case-control...
Topics
- Adult
- Aged
- Case-Control Studies
- Cytochrome P-450 CYP1A1
- DNA
- Female
- Genetic Predisposition to Disease
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Prevalence
- Risk Factors
- Turkey
- White People
