Article
Polymorphism of the CYP1A1 and glutathione-S-transferase gene in Korean lung cancer patients.
Experimental & molecular medicine - 31 Dec 1998
Hong Y S, Chang J H, Kwon O J, Ham Y A, Choi J H
Abstract excerpt
The levels of expressions and catalytic activities of cytochrome P450 (CYP1A1) and glutathione-S-transferase class mu (GSTM1) enzymes in lungs and their metabolic balance may be an important determinant host factor underlying lung cancer. Genetic differences in metabolism, MspI restriction sites,...
Topics
- Adenocarcinoma
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Cytochrome P-450 CYP1A1
- Gene Frequency
- Genotype
- Glutathione Transferase
- Humans
- Korea
- Linkage Disequilibrium
- Lung Neoplasms
- Mutation