CYP1A1 polymorphisms and lung cancer risk: a meta-analysis.

doi:10.1097/00008571-200003000-00002

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Article

CYP1A1 polymorphisms and lung cancer risk: a meta-analysis.

Pharmacogenetics - 1 Mar 2000

Houlston R S

Abstract excerpt

To examine the risk of lung cancer associated with the MspI-restriction fragment length polymorphism and Exon7-Val polymorphisms of CYP1A1, a meta-analysis of published case-control studies was undertaken using a random effects model. The principal outcome measure was the odds ratio for the risk of lung cancer, using homozygosity of the 'wild-type allele' as the reference group. Fifteen reports detailing the...

Topics

Adult
Aged
Aged, 80 and over
Cytochrome P-450 CYP1A2
Deoxyribonuclease HpaII
Female
Genetic Predisposition to Disease
Humans
Isoleucine
Leucine
Lung Neoplasms
Male
Middle Aged
Polymorphism, Genetic
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 10761998
DOI: 10.1097/00008571-200003000-00002

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