Article
Deletions on the long arm of chromosome 17 in pilocytic astrocytoma.
Acta neuropathologica - 1 Jan 1993
von Deimling A, Louis D N, Menon A G, von Ammon K, Petersen I, Ellison D, Wiestler O D, Seizinger B R
Abstract excerpt
Pilocytic astrocytomas are the most common astrocytic tumors of childhood and differ clinically and histopathologically from those astrocytomas that affect adults. Studies of adult astrocytic tumors have revealed allelic losses on chromosomes 10, 17p, 19q and alterations in the epidermal growth f...
Topics
- Adolescent
- Adult
- Alleles
- Astrocytoma
- Autoradiography
- Brain Neoplasms
- Child
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- DNA Probes
- Female
- Genes, Neurofibromatosis 1
- Humans
- Male
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
