Article
Allelic gain and amplification on the long arm of chromosome 17 in anaplastic meningiomas.
Brain pathology (Zurich, Switzerland) - 1 Apr 2002
Büschges Rainer, Ichimura Koichi, Weber Ruthild G, Reifenberger Guido, Collins V Peter
Abstract excerpt
Using comparative genomic hybridization (CGH) we have previously identified amplification at 17q21-qter as a common aberration in anaplastic meningiomas but not in atypical or benign meningiomas (19). To define the amplified genomic region, we analyzed 44 meningeal tumors, including 7 benign meningiomas of World Health Organization (WHO) grade 1,19 atypical meningiomas (WHO grade II) and 18 anaplastic meningiomas...
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