Molecular genetics of pediatric brain stem gliomas. Application of PCR techniques to small and archival brain tumor specimens.

doi:10.1097/00005072-199309000-00009

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Article

Molecular genetics of pediatric brain stem gliomas. Application of PCR techniques to small and archival brain tumor specimens.

Journal of neuropathology and experimental neurology - 1 Sept 1993

Louis D N, Rubio M P, Correa K M, Gusella J F, von Deimling A

Abstract excerpt

Brain stem gliomas are pediatric astrocytomas that histologically resemble adult supratentorial astrocytomas such as glioblastomas multiforme (GBM). Our molecular genetic studies have suggested that adult GBM can be divided into two genetic subsets: tumors with p53 tumor suppressor gene mutations...

Topics

Adolescent
Alleles
Astrocytoma
Base Sequence
Brain Neoplasms
Brain Stem
Child
Child, Preschool
Chromosome Aberrations
Chromosome Mapping
Chromosomes, Human, Pair 10
Codon
DNA, Neoplasm
Exons
Female
Genes, p53
Glioma
Humans

Source

Open in PubMed

Identifiers

PMID: 8103086
DOI: 10.1097/00005072-199309000-00009

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8103086-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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