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Article

Molecular genetics of pediatric brain stem gliomas. Application of PCR techniques to small and archival brain tumor specimens.

Journal of neuropathology and experimental neurology - 1 Sept 1993

Louis D N, Rubio M P, Correa K M, Gusella J F, von Deimling A

Abstract excerpt

Brain stem gliomas are pediatric astrocytomas that histologically resemble adult supratentorial astrocytomas such as glioblastomas multiforme (GBM). Our molecular genetic studies have suggested that adult GBM can be divided into two genetic subsets: tumors with p53 tumor suppressor gene mutations and chromosome 17p loss that occur more commonly in younger patients; and tumors with epidermal growth factor receptor...

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Source

Identifiers

PMID: 8103086
DOI: 10.1097/00005072-199309000-00009

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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