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Article

Chromosome localization and RFLP analysis of PDC-E2: the major autoantigen of primary biliary cirrhosis.

Autoimmunity - 1 Jan 1993

Leung P S, Watanabe Y, Munoz S, Teuber S S, Patel M S, Korenberg J R, Hara P, Coppel R, Gershwin M E

Abstract excerpt

Patients with primary biliary cirrhosis are well known for the presence of titer antibodies against dihydrolipoamide acetyltransferase, the E2 subunit of the pyruvate dehydrogenase complex. We have taken advantage of a cDNA probe for dihydrolipoamide acetyltransferase to explore the possibility of polymorphism of the E2 subunit by probing genomic DNA from 38 patients with primary biliary cirrhosis and 26 healthy...

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Share to Autoantigens
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 11

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Share to Liver Cirrhosis, Biliary

Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 8102256
DOI: 10.3109/08916939309079237

Genes

PDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Chromosome localization and RFLP analysis of PDC-E2: the major autoantigen of primary biliary cirrhosis.PMID 8102256Read ↗

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