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Article

Genetic factors in conditioned tolerance to the analgesic effects of etonitazene.

Pharmacology, biochemistry, and behavior - 1 May 1993

Elmer G I, Mathura C B, Goldberg S R

Abstract excerpt

Tolerance to the analgesic effects of opioids have been reported to include unconditioned (physiological) and conditioned (associative) components. The purpose of the current study was to investigate the genetic and environmental factors important in the development of tolerance by using three inbred strains of mice with varying opiate receptor concentration and acute behavioral response to opioids: C57BL/6J,...

Topics

Analgesics
Animals
Benzimidazoles
Conditioning, Psychological
Drug Tolerance
Genotype
Male
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Pain Measurement
Species Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8100074
DOI: 10.1016/0091-3057(93)90115-a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8100074-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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