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Article

Intravenous fentanyl self-administration in male and female C57BL/6J and DBA/2J mice.

Scientific reports - 16 Jan 2023

Leonardo Michael, Brunty Sarah, Huffman Jessica, Kastigar Alexis, Dickson Price E

Abstract excerpt

The genetic mechanisms underlying fentanyl addiction, a highly heritable disease, are unknown. Identifying these mechanisms will lead to better risk assessment, early diagnosis, and improved intervention. To this end, we used intravenous fentanyl self-administration to quantify classical self-administration phenotypes and addiction-like fentanyl seeking in male and female mice from the two founder strains of the...

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Identifiers

PMID: 36646781
DOI: 10.1038/s41598-023-27992-8
PMCID: PMC9842734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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