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Article

Genetic variance in nociception and its relationship to the potency of morphine-induced analgesia in thermal and chemical tests.

Pain - 1 Mar 1998

Elmer Gregory I, Pieper Jeanne O, Negus Stevens S, Woods James H

Abstract excerpt

The perceived intensity of a painful stimulus is determined in part by the stimulus intensity and environmental conditions. The purpose of this study was to determine the influence of genetic factors in nociception and its contribution to the potency of morphine to produce antinociception. Eight inbred strains of mice were tested across a range of stimulus intensities in thermal (hot plate) and chemical irritant...

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Identifiers

PMID: 9539682
DOI: 10.1016/S0304-3959(97)00215-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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