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Article

Genomic modifications in naturally occurring neurovirulent revertants of Sabin 1 polioviruses.

Developments in biological standardization - 1 Jan 1993

Otelea D, Guillot S, Furione M, Combiescu A A, Balanant J, Candrea A, Crainic R

Abstract excerpt

Five type 1 Sabin-like poliovirus strains were isolated from paralytic cases of poliomyelitis. Their Sabin origin was confirmed by antigenic analysis with monoclonal antibodies and restriction fragment length polymorphism (RFLP) assay. Several nucleotide positions known to play a role in the reversion towards neurovirulence were examined: viz 480, 2741, 6203, 7441. Analysis was performed by enzymatic restriction...

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Identifiers

PMID: 8099049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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