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Article

Genomic modifications in naturally occurring neurovirulent revertants of Sabin 1 polioviruses.

Developments in biological standardization - 1 Jan 1993

Otelea D, Guillot S, Furione M, Combiescu A A, Balanant J, Candrea A, Crainic R

Abstract excerpt

Five type 1 Sabin-like poliovirus strains were isolated from paralytic cases of poliomyelitis. Their Sabin origin was confirmed by antigenic analysis with monoclonal antibodies and restriction fragment length polymorphism (RFLP) assay. Several nucleotide positions known to play a role in the reve...

Topics

Humans
Infant
Mutation
Poliomyelitis
Poliovirus
Poliovirus Vaccine, Oral
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
RNA, Viral
Virulence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8099049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8099049-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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