Article
Use of mutational pattern in 5'-NCR and VP1 regions of polioviruses for molecular diagnosis.
Molecular and cellular probes - 1 Aug 2007
Pliaka V, Dedepsidis E, Kyriakopoulou Z, Papadopoulou I, Levidiotou S, Markoulatos P
Abstract excerpt
Polioviruses are members of the enterovirus genus, belonging to the Picornaviridae family. They are the causative agents of poliomyelitis, a paralytic and sometimes fatal disease in humans. The number of poliomyelitis cases caused by wild poliovirus infections has been dramatically reduced by the...
Topics
- Amino Acid Sequence
- Base Sequence
- Capsid
- Child
- Child, Preschool
- DNA, Viral
- Genotype
- Humans
- Infant
- Molecular Sequence Data
- Mutagenesis
- Mutation
- Nucleic Acid Conformation
- Poliomyelitis
- Poliovirus
- Poliovirus Vaccine, Oral
- Polymorphism, Restriction Fragment Length
- Sequence Analysis, DNA
