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Article

Changes in population dynamics during long-term evolution of sabin type 1 poliovirus in an immunodeficient patient.

Journal of virology - 1 Sept 2008

Odoom John K, Yunus Zaira, Dunn Glynis, Minor Philip D, Martín Javier

Abstract excerpt

The evolution of the Sabin strain of type 1 poliovirus in a hypogammaglobulinemia patient for a period of 649 days is described. Twelve poliovirus isolates from sequential stool samples encompassing days 21 to 649 after vaccination with Sabin 1 were characterized in terms of their antigenic properties, virulence in transgenic mice, sensitivity for growth at high temperatures, and differences in nucleotide...

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Identifiers

PMID: 18596089
DOI: 10.1128/JVI.00468-08
PMCID: PMC2546908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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