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Article

Correlation of mutations and recombination with growth kinetics of poliovirus vaccine strains.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Dec 2010

Pliaka V, Kyriakopoulou Z, Tsakogiannis D, Ruether I G A, Gartzonika C, Levidiotou-Stefanou S, Krikelis A, Markoulatos P

Abstract excerpt

Attenuated strains of Sabin poliovirus vaccine replicate in the human gut and, in rare cases, may cause vaccine-associated paralytic poliomyelitis (VAPP). The genetic instability of Sabin strains constitutes one of the main causes of VAPP, a disease that is most frequently associated with type 3 and type 2 Sabin strains, and more rarely with type 1 Sabin strains. In the present study, the growth phenotype of...

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Identifiers

PMID: 20820837
DOI: 10.1007/s10096-010-1033-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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