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Article

Posttranslational N-glycosylation takes place during the normal processing of human coagulation factor VII.

Glycobiology - 1 May 2005

Bolt Gert, Kristensen Claus, Steenstrup Thomas Dock

Abstract excerpt

N-glycosylation is normally a cotranslational process that occurs during translocation of the nascent protein to the endoplasmic reticulum. In the present study, however, we demonstrate posttranslational N-glycosylation of recombinant human coagulation factor VII (FVII) in CHO-K1 and 293A cells. Human FVII has two N-glycosylation sites (N145 and N322). Pulse-chase labeled intracellular FVII migrated as two bands...

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Identifiers

PMID: 15616124
DOI: 10.1093/glycob/cwi032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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