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Article

Glycosylation and phosphorylation of lysosomal glycosylasparaginase.

Archives of biochemistry and biophysics - 1 Apr 1996

Park H, Vettese-Dadey M, Aronson N N

Abstract excerpt

Glycosylasparaginase (EC 3.5.1.26) is a lysosomal amidase which hydrolyzes the bond between asparagine and the sugar moiety in N-linked glycoproteins. Deficiency of the enzyme results in aspartylglycosaminuria (AGU), the most common disorder of glycoprotein degradation. Mature enzyme is formed by two proteolytic cleavage steps subsequent to removal of its signal peptide: (1) an activation cleavage in the ER of...

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Identifiers

PMID: 8638940
DOI: 10.1006/abbi.1996.0144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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