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Article

Role of N-glycosylation in cathepsin E. A comparative study of cathepsin E with distinct N-linked oligosaccharides and its nonglycosylated mutant.

European journal of biochemistry - 1 Dec 1999

Yasuda Y, Ikeda S, Sakai H, Tsukuba T, Okamoto K, Nishishita K, Akamine A, Kato Y, Yamamoto K

Abstract excerpt

Cathepsin E (CE), a nonlysosomal, intracellular aspartic proteinase, exists in several molecular forms that are N-glycosylated with high-mannose and/or complex-type oligosaccharides. To investigate the role of N-glycosylation on the catalytic properties and molecular stability of CE, both natural and recombinant enzymes with distinct oligosaccharides were purified from different sources. An N-glycosylation minus...

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PMID: 10561578
DOI: 10.1046/j.1432-1327.1999.00863.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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