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Article

DNA polymerase delta is required for base excision repair of DNA methylation damage in Saccharomyces cerevisiae.

Proceedings of the National Academy of Sciences of the United States of America - 13 Sept 1994

Blank A, Kim B, Loeb L A

Abstract excerpt

We present evidence that DNA polymerase delta of Saccharomyces cerevisiae, an enzyme that is essential for viability and chromosomal replication, is also required for base excision repair of exogenous DNA methylation damage. The large catalytic subunit of DNA polymerase delta is encoded by the CDC2(POL3) gene. We find that the mutant allele cdc2-2 confers sensitivity to killing by methyl methanesulfonate (MMS)...

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Identifiers

PMID: 8090767
DOI: 10.1073/pnas.91.19.9047
PMCID: PMC44744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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DNA polymerase delta is required for base excision repair of DNA methylation damage in Saccharomyces cerevisiae.PMID 8090767Read ↗

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MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae.Semantic proximity Read ↗

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Mutations in the Non-Catalytic Subunit Dpb2 of DNA Polymerase Epsilon Affect the Nrm1 Branch of the DNA Replication Checkpoint.Semantic proximity Read ↗

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Involvement of the yeast DNA polymerase delta in DNA repair in vivo.Semantic proximity Read ↗

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