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Article

MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae.

Molecular genetics and genomics : MGG - 1 Jan 2002

Hryciw T, Tang M, Fontanie T, Xiao W

Abstract excerpt

A series of yeast mutants were isolated that are sensitive to killing by the monofunctional DNA-alkylating agent methyl methanesulfonate (MMS) but not by UV or X-radiation. We have cloned and characterized one of the corresponding genes, MMS1, and show that the mms1 Delta mutant is dramatically sensitive to killing by MMS and mildly sensitive to UV radiation. mms1 Delta mutants display an elevated level of...

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Share to DNA Damage
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epistasis, Genetic

Share to Genes, Fungal

Share to Methyl Methanesulfonate

Share to Rad52 DNA Repair and Recombination Protein

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Source

Identifiers

PMID: 11810260
DOI: 10.1007/s00438-001-0605-x

Genes

RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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