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Article

DNA polymerase 4 of Saccharomyces cerevisiae is important for accurate repair of methyl-methanesulfonate-induced DNA damage.

Genetics - 1 Jan 2006

Sterling Catherine H, Sweasy Joann B

Abstract excerpt

The DNA polymerase 4 protein (Pol4) of Saccharomyces cerevisiae is a member of the X family of DNA polymerases whose closest human relative appears to be DNA polymerase lambda. Results from previous genetic studies conflict over the role of Pol4 in vivo. Here we show that deletion of Pol4 in a diploid strain of the SK1 genetic background results in sensitivity to methyl methanesulfonate (MMS). However, deletion...

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Identifiers

PMID: 16219787
DOI: 10.1534/genetics.105.049254
PMCID: PMC1456199

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Source receipt: pubmed, retrieved 7 Sept 2026.

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