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Article

Cell-cycle and DNA damage regulation of the DNA mismatch repair protein Msh2 occurs at the transcriptional and post-transcriptional level.

DNA repair - 1 Feb 2013

Tennen Ruth I, Haye Joanna E, Wijayatilake Hashanthi D, Arlow Tim, Ponzio Danielle, Gammie Alison E

Abstract excerpt

DNA mismatch repair during replication is a conserved process essential for maintaining genomic stability. Mismatch repair is also implicated in cell-cycle arrest and apoptosis after DNA damage. Because yeast and human mismatch repair systems are well conserved, we have employed the budding yeast Saccharomyces cerevisiae to understand the regulation and function of the mismatch repair gene MSH2. Using a...

Topics

Base Sequence
Cell Cycle
Codon, Initiator
Codon, Terminator
DNA Damage
DNA Mismatch Repair
DNA, Fungal
Gene Expression Regulation, Fungal
Methyl Methanesulfonate
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

MutS Homolog 2 Protein

Mutation

Open Reading Frames

RNA Stability

RNA, Messenger

Response Elements

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 23261051
DOI: 10.1016/j.dnarep.2012.11.002
PMCID: PMC3749301

Genes

MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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Cell-cycle and DNA damage regulation of the DNA mismatch repair protein Msh2 occurs at the transcriptional and post-transcriptional level.PMID 23261051Read ↗

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