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Article

Involvement of the yeast DNA polymerase delta in DNA repair in vivo.

Genetics - 1 Aug 1997

Giot L, Chanet R, Simon M, Facca C, Faye G

Abstract excerpt

The POL3 encoded catalytic subunit of DNA polymerase delta possesses a highly conserved C-terminal cysteine-rich domain in Saccharomyces cerevisiae. Mutations in some of its cysteine codons display a lethal phenotype, which demonstrates an essential function of this domain. The thermosensitive mutant pol3-13, in which a serine replaces a cysteine of this domain, exhibits a range of defects in DNA repair, such as...

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Identifiers

PMID: 9258670
DOI: 10.1093/genetics/146.4.1239
PMCID: PMC1208071

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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