Article
Elevated expression of the junB proto-oncogene is essential for v-fos induced transformation of Rat-1 cells.
Oncogene - 1 Oct 1994
Van Amsterdam J R, Wang Y, Sullivan R C, Zarbl H
Abstract excerpt
We previously described the isolation of non-tumorigenic revertants from mutagenized populations of v-fos-transformed Rat-1 cells (Zarbl et al., 1987). In the present study we examined the possibility that the revertant phenotype resulted from mutations that altered the expression or activities of the c-jun or junB proto-oncogenes. The results demonstrated that levels of the c-jun mRNA and protein were unchanged...
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