Article
Elevated expression of the junB proto-oncogene is essential for v-fos induced transformation of Rat-1 cells.
Oncogene - 1 Oct 1994
Van Amsterdam J R, Wang Y, Sullivan R C, Zarbl H
Abstract excerpt
We previously described the isolation of non-tumorigenic revertants from mutagenized populations of v-fos-transformed Rat-1 cells (Zarbl et al., 1987). In the present study we examined the possibility that the revertant phenotype resulted from mutations that altered the expression or activities o...
Topics
- Alleles
- Animals
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Cells, Cultured
- Gene Expression
- Genes, jun
- Oncogene Proteins v-fos
- Proto-Oncogene Proteins c-jun
- RNA, Antisense
- Rats