Article
Reversion of Ras transformed cells by Ets transdominant mutants.
Oncogene - 1 Dec 1994
Wasylyk C, Maira S M, Sobieszczuk P, Wasylyk B
Abstract excerpt
Considerable progress has been made in elucidating the components of the Ras signalling pathway, from both biochemical and genetic investigations. However little is known about the nuclear targets of the pathway, and in particular those that mediate the long-term changes in gene expression result...
Topics
- 3T3 Cells
- Agar
- Animals
- Blood
- Cathepsin L
- Cathepsins
- Cell Transformation, Neoplastic
- Cysteine Endopeptidases
- Endopeptidases
- Genes, Dominant
- Genes, Retinoblastoma
- Genes, p53
- Genes, ras
- Mice
- Mutation
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-ets
- RNA, Messenger