Article
Inhibition of tumorigenicity of a murine squamous cell carcinoma (SCC) cell line by a putative tumor suppressor gene on human chromosome 7.
Oncogene - 1 Oct 1994
Zenklusen J C, Oshimura M, Barrett J C, Conti C J
Abstract excerpt
Alterations in oncogenes and tumor suppressor genes (TSG) are considered to be critical steps in oncogenesis. However information on putative TSG involved in the development of squamous cell carcinomas (SCC) is very limited. In this study we confirmed the existence of a tumor suppressor gene (TSG) on human chromosome 7 (hchr 7) that suppresses the tumorigenicity of squamous cell carcinomas (SCCs). We injected...
Topics
- Animals
- Carcinoma, Squamous Cell
- Cell Division
- Cell Fusion
- Chromosomes, Human, Pair 12
- Chromosomes, Human, Pair 7
- Female
- Genes, Tumor Suppressor
- Humans
- In Situ Hybridization
- Mice
