Expression of intermediate filament proteins in TPA-induced MPC-11 and HL-60 cells.

doi:10.1016/0014-4827(92)90446-f

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Article

Expression of intermediate filament proteins in TPA-induced MPC-11 and HL-60 cells.

Experimental cell research - 1 Apr 1992

Paulin-Levasseur M, Julien M

Abstract excerpt

Under normal culture conditions, the tumor cell lines MPC-11 and HL-60 exhibit high rates of proliferation and show a peculiar expression of intermediate filament proteins as they appear to synthesize only lamin B. A 48-h exposure of murine plasmacytomas MPC-11 to the phorbol ester TPA reduces their growth and induces vimentin synthesis without affecting the composition of their nuclear lamina. When applied to...

Topics

Animals
Blotting, Western
Cell Differentiation
Cell Division
Fluorescent Antibody Technique
Humans
Intermediate Filament Proteins
Kinetics
Lamin Type A
Lamin Type B
Lamins
Leukemia, Promyelocytic, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Nuclear Proteins

Phenotype

Plasmacytoma

Tetradecanoylphorbol Acetate

Thymidine

Source

Open in PubMed

Identifiers

PMID: 1544377
DOI: 10.1016/0014-4827(92)90446-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1544377-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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