PCR-based CYP2D6 genotyping for Finnish lung cancer patients.

doi:10.1097/00008571-199302000-00002

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Article

PCR-based CYP2D6 genotyping for Finnish lung cancer patients.

Pharmacogenetics - 1 Feb 1993

Hirvonen A, Husgafvel-Pursiainen K, Anttila S, Karjalainen A, Pelkonen O, Vainio H

Abstract excerpt

Polymorphism of the gene encoding for debrisoquine hydroxylase, i.e. CYP2D6, was determined genotypically for 122 healthy controls and 106 lung cancer patients using Xba I restriction fragment length polymorphism (RFLP) analysis, together with a combination of two recently published polymerase chain reaction (PCR) based approaches. Three different mutated alleles of the CYP2D6 gene were detected; CYP2D6B...

Topics

Aged
Alleles
Base Sequence
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
DNA Mutational Analysis
DNA, Neoplasm
Debrisoquin
Female
Finland
Gene Frequency
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Lung Neoplasms

Male

Middle Aged

Mixed Function Oxygenases

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 8097947
DOI: 10.1097/00008571-199302000-00002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8097947-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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