Article
Human CYP2D6 gene polymorphism in Slovene cancer patients and healthy controls.
Carcinogenesis - 1 Nov 1995
Dolzan V, Rudolf Z, Breskvar K
Abstract excerpt
The polymorphic CYP2D6 gene encoding debrisoquine hydroxylase has attracted much interest for its possible role in human pulmonary carcinogenesis. The purpose of this work was to determine the frequency of poor metabolizers (PM) and extensive metabolizers (EM) of debrisoquine in Slovene population of healthy individuals (n = 107), lung cancer patients (200) and melanoma patients (121). Polymorphism of CYP2D6 gene...
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