Human CYP2D6 gene polymorphism in Slovene cancer patients and healthy controls.

doi:10.1093/carcin/16.11.2675

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Article

Human CYP2D6 gene polymorphism in Slovene cancer patients and healthy controls.

Carcinogenesis - 1 Nov 1995

Dolzan V, Rudolf Z, Breskvar K

Abstract excerpt

The polymorphic CYP2D6 gene encoding debrisoquine hydroxylase has attracted much interest for its possible role in human pulmonary carcinogenesis. The purpose of this work was to determine the frequency of poor metabolizers (PM) and extensive metabolizers (EM) of debrisoquine in Slovene populatio...

Topics

Adult
Aged
Alleles
Cytochrome P-450 CYP2D6
Cytochrome P-450 Enzyme System
Female
Humans
Lung Neoplasms
Male
Melanoma
Middle Aged
Mixed Function Oxygenases
Polymorphism, Genetic

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