Article
Frequency of the variant allele CYP2D6(C) among North American Caucasian lung cancer patients and controls.
Lung cancer (Amsterdam, Netherlands) - 1 May 1997
Shaw G L, Weiffenbach B, Falk R T, Frame J N, Issaq H J, Moir D T, Caporaso N
Abstract excerpt
Previous reports of the association between the debrisoquine polymorphism and lung cancer risk are conflicting. Following the report of an association between lung cancer risk and the variant allele CYP2D6(C), we examined the presence of this allele in 98 incident Caucasian lung cancer patients a...
Topics
- Alleles
- Carcinoma, Small Cell
- Carcinoma, Squamous Cell
- Case-Control Studies
- Cytochrome P-450 CYP2D6
- Debrisoquin
- Female
- Gene Frequency
- Genetic Variation
- Genotype
- Heterozygote
- Homozygote
- Humans
- Lung Neoplasms
- Male
- North America
- Phenotype
- Pregnancy