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Article

Molecular analysis of the retinoblastoma gene in primary ovarian cancer cells.

International journal of cancer - 1 Sept 1994

Liu Y, Heyman M, Wang Y, Falkmer U, Hising C, Székely L, Einhorn S

Abstract excerpt

Loss of heterozygosity (LOH) at the site of the retinoblastoma (RB1) gene, at 13q14, has been shown to occur in a high proportion of ovarian cancer patients. Based on this, RB1 gene inactivation was studied in primary tumor cells from 15 patients with ovarian cancer. Structural changes as well as expression of the RB1 gene were investigated. One patient had a nondisjunctional deletion at the RB1 locus, and the...

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Identifiers

PMID: 8077050
DOI: 10.1002/ijc.2910580508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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