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Article

Alterations of the retinoblastoma gene in metastatic breast cancer.

Clinical & experimental metastasis - 1 Mar 2011

Berge Elisabet Ognedal, Knappskog Stian, Lillehaug Johan Richard, Lønning Per Eystein

Abstract excerpt

Germline mutations affecting the retinoblastoma gene (RB1) predispose to inherited retinoblastomas but also other malignancies, including breast cancer. While somatic RB1 mutations have been detected in different malignancies, information about the potential role of RB1 mutations in breast cancer is limited. Recently, we discovered RB1 mutations to be associated with resistance to anthracyclines/mitomycin in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21253829
DOI: 10.1007/s10585-011-9375-y
PMCID: PMC3040352

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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