Article
The yeast centrin, cdc31p, and the interacting protein kinase, Kic1p, are required for cell integrity.
The Journal of cell biology - 2 Nov 1998
Sullivan D S, Biggins S, Rose M D
Abstract excerpt
Cdc31p is the yeast homologue of centrin, a highly conserved calcium-binding protein of the calmodulin superfamily. Previously centrins have been implicated only in microtubule-based processes. To elucidate the functions of yeast centrin, we carried out a two-hybrid screen for Cdc31p-interacting proteins and identified a novel essential protein kinase of 1,080 residues, Kic1p (kinase that interacts with Cdc31p)....
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