Article
Involvement of aberrant p53 expression and human papillomavirus in carcinoma of the head, neck and esophagus.
Anticancer research - 1 Jan 2000
Lewensohn-Fuchs I, Munck-Wikland E, Berke Z, Magnusson K P, Pallesen G, Auer G, Lindholm J, Linde A, Aberg B, Rubio C, Kuylenstierna R, Wiman K G, Dalianis T
Abstract excerpt
Biopsies from 34 patients with cancer of the head, neck or esophagus, 2 laryngeal papillomas, and 2 normal tonsils were analysed for human papillomavirus (HPV), Epstein Barr virus (EBV) genomes and mutated or elevated levels of p53. In 4 biopsies p53 was also analysed by DNA sequencing. HPV type 31 was found in one laryngeal cancer with normal p53 and HPV type 16 in two tonsil cancers with aberrant p53...
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