Article
Involvement of aberrant p53 expression and human papillomavirus in carcinoma of the head, neck and esophagus.
Anticancer research - 1 Jan 2000
Lewensohn-Fuchs I, Munck-Wikland E, Berke Z, Magnusson K P, Pallesen G, Auer G, Lindholm J, Linde A, Aberg B, Rubio C, Kuylenstierna R, Wiman K G, Dalianis T
Abstract excerpt
Biopsies from 34 patients with cancer of the head, neck or esophagus, 2 laryngeal papillomas, and 2 normal tonsils were analysed for human papillomavirus (HPV), Epstein Barr virus (EBV) genomes and mutated or elevated levels of p53. In 4 biopsies p53 was also analysed by DNA sequencing. HPV type...
Topics
- Base Sequence
- Carcinoma, Squamous Cell
- Esophageal Neoplasms
- Follow-Up Studies
- Head and Neck Neoplasms
- Herpesvirus 4, Human
- Humans
- Molecular Sequence Data
- Mutation
- Papillomaviridae
- Polymerase Chain Reaction
- Tumor Suppressor Protein p53